Understanding oncogene driven cell migration in vivo

A focus of our group has been the study of Stit, Drosophila RET, its role in cell migration and novel observations made by the lab earlier 1. We use Drosophila melanogaster, where we can overexpress and/or knock down a gene of interest in a specific area within an epithelial tissue using the GAL4/UAS expression system. Read More …

Transgenic tools for studying the nervous system in Nematostella vectensis

Cnidarians (nessledyr) lack a centralized nervous system but they are able to produce large numbers of neurons throughout their life and in all tissues. How these neurons find other cells to which they connect, is not known. To understand this process better, we have generated transgenic sea anemones in which actin filaments, microtubules or the Read More …